I use Win 10 almost every day for testing. Gabe, (thanks again for multiple tutorials) use Win 10 on his PC. Francesco van Loon (our expert and the man who did multiple Pangolin trainings) use mostly Win 10 on his computers. I saw Win 10 and BEYOND in permanent installations, where application runs all the time. I am not aware of Win 10 related problems. However, if your computer works fine with current version of Windows, then it is a question - update or no.
Regards,
Alexey